Brain markers predicting response to cognitive-behavioral therapy for social anxiety disorder: An independent replication of Whitfield-Gabrieli et al. 2015
Ashar, Y.K., Clark, J., Gunning, F. M., Goldin, P., Gross, J. J., & Wager, T.D.
In one sentence. Attempted an independent replication of a resting-state amygdala-connectivity marker predicting cognitive-behavioral therapy response in social anxiety disorder and found only marginal, much weaker prediction than in the original report.
Abstract
Predictive brain markers promise a number of important scientific, clinical, and societal applications. Over 600 predictive brain markers have been described in published reports, but very few have been tested in independent replication attempts. Here, we conducted an independent replication of a previously published marker predicting treatment response to cognitive-behavioral therapy for social anxiety disorder from patterns of resting-state fMRI amygdala connectivity
Citation: Ashar, Y.K., Clark, J., Gunning, F. M., Goldin, P., Gross, J. J., & Wager, T.D. (2021). Brain markers predicting response to cognitive-behavioral therapy for social anxiety disorder: An independent replication of Whitfield-Gabrieli et al. 2015. Translational Psychiatry, 11(1), 260. https://doi.org/10.1038/s41398-021-01366-y