Pain reprocessing therapy vs placebo and usual care for patients with chronic back pain: 5-year follow-up of a randomized clinical trial: 5-year follow-up of a randomized clinical trial
Ashar, Y. K., Low, E. L., Knight, K., Schubiner, H., Gordon, A., LeRoux, A., Lumley, M. A., & Wager, T. D.
In one sentence. In a 5-year follow-up of a randomized trial comparing pain reprocessing therapy, placebo, and usual care for chronic back pain, participants who received pain reprocessing therapy reported significantly lower pain intensity and greater improvement in pain interference, depression, and mind-brain pain attributions.
Abstract
This secondary analysis of a randomized clinical trial provided 5-year follow-up data for individuals with chronic back pain treated with pain reprocessing therapy, placebo, or usual care.
Citation: Ashar, Y. K., Low, E. L., Knight, K., Schubiner, H., Gordon, A., LeRoux, A., Lumley, M. A., & Wager, T. D. (2025). Pain reprocessing therapy vs placebo and usual care for patients with chronic back pain: 5-year follow-up of a randomized clinical trial: 5-year follow-up of a randomized clinical trial. JAMA Psychiatry (Chicago, Ill.), 82(10), 1049–1051, 82(10), 1049. https://doi.org/10.1001/jamapsychiatry.2025.1844